Parkinson’s Disease Psychosis

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REM sleep behavior disorder

Minor hallucinations occur in drug-naive Parkinson’s disease patients, even from the premotor phase

By Javier Pagonabarraga MD, PhD, Saul Martinez-Horta BSc, Ramón Fernández de Bobadilla BSc, Jesús Pérez MD, Roser Ribosa-Nogué MD, Juan Marín MD, Berta Pascual-Sedano MD, PhD, Carmen García BSc, PhD, Alexandre Gironell MD, PhD and Jaime Kulisevsky MD, PhD

Objectives The description of minor hallucinatory phenomena (presence, passage hallucinations) has widened the spectrum of psychosis in Parkinson’s disease (PD). Minor hallucinatory phenomena seem to antedate the development of more severe hallucinations. Early detection of minor hallucinations may be useful for screening patients with more severe endophenotypes. Motivated by the observation of “de novo,” drug-naive…

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